Understanding Mycoplasma Pneumonia (Walking Pneumonia) in Children: Signs, Symptoms, and Treatment

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As pediatricians, we often encounter cases of respiratory infections that are usually mild, but certain ones, like Mycoplasma pneumonia (often called “walking pneumonia”), can sometimes develop into something more serious. Mycoplasma pneumonia is a type of atypical pneumonia commonly seen in school-aged children and young adults, and it’s important for parents to know the basics about it. Here, we’ll cover the signs, symptoms, how it spreads, and when to seek treatment.

What is Mycoplasma Pneumonia?

Mycoplasma pneumonia is a bacterial infection that usually affects the respiratory system. Unlike traditional pneumonia, which can cause severe symptoms requiring immediate intervention, Mycoplasma pneumonia is often mild, resembling an upper respiratory infection (URI) more than a typical pneumonia. This mild nature is why it’s sometimes referred to as “walking pneumonia.” While most children with Mycoplasma experience minor symptoms, in certain cases, the infection can progress to a more severe form, making early recognition helpful.

Signs and Symptoms

In children, the signs and symptoms of Mycoplasma pneumonia can vary, but they often include:

  • Persistent dry cough: This is one of the most common symptoms and may last for weeks.
  • Sore throat: Children may experience a mild sore throat, similar to that of a common cold.
  • Low-grade fever: Fever is usually mild but can occasionally spike.
  • Fatigue and weakness: Children may feel tired or listless even if their symptoms appear mild.
  • Headaches and body aches: These are more common in older children and adolescents.

Though symptoms often start mild, parents should be on alert if a persistent cough, shortness of breath, or fever that doesn’t improve develops, as these could indicate the infection is becoming more serious.

How is Mycoplasma Pneumonia Spread?

Mycoplasma pneumonia is spread through respiratory droplets, meaning it can be passed from one person to another through coughing, sneezing, or even talking in close quarters. This makes schools and daycare centers common places where the infection can spread quickly among children. It is also more common during colder months, as children are indoors and in closer contact with each other.

Treatment: Does It Always Require Antibiotics?

The good news for parents is that most cases of Mycoplasma pneumonia in children are mild and may not require antibiotics. Typically, symptoms resolve on their own with rest, hydration, and supportive care. However, in some cases where symptoms persist or worsen, your pediatrician may consider an antibiotic. While many bacterial infections require specific antibiotics, Mycoplasma pneumonia is unique in that it often responds well to a commonly prescribed antibiotic called azithromycin, or a “Z-Pack.” Azithromycin can quickly reduce symptoms and speed up recovery when necessary.

When to Seek Medical Advice

While Mycoplasma pneumonia often resembles a cold, if your child has symptoms that worsen or last beyond a week, it may be best to consult your pediatrician. Other red flags to watch for include:

  • Persistent high fever
  • Shortness of breath or difficulty breathing
  • Severe cough that worsens over time
  • Noticeable fatigue affecting your child’s daily activities

Prevention Tips

Because Mycoplasma pneumonia spreads easily in group settings, encourage children to practice good hygiene, especially during cold and flu season. Regular handwashing, covering coughs and sneezes, and avoiding close contact with those who are sick can all help reduce the risk of infection.

In summary, while Mycoplasma pneumonia is typically mild and often goes away on its own, it can sometimes lead to more severe respiratory issues. By recognizing the signs early and understanding when antibiotics like azithromycin may be helpful, parents can feel confident in managing their child’s health this cold season. For any questions or concerns, feel free to reach out to our office—our team is here to help you and your family stay healthy!

How to Minimize Vaccine Reactions for Your Child: Tips for Parents

(General Health Maintenance and OTC and/or Prescription Medication)

    Vaccinations are essential for keeping your child safe from serious illnesses, but it’s natural to worry about how they might feel afterward. While most vaccine side effects are mild and short-lived (though I have personally seen more severe reactions, such as seizures, seizure-like activity, and temporary loss of developmental milestones), there are steps you can take to help minimize inflammation and any discomfort and ensure your child feels their best. Here’s what you can do before and after your child’s vaccination to help reduce potential reactions.

    1. Keep Your Child Hydrated

    Making sure your child is well-hydrated before their vaccine can make a big difference. Encourage them to drink water throughout the day leading up to their appointment. Staying hydrated helps their body respond effectively to the vaccine and can also reduce the chance of feeling lightheaded afterward.

    2. Offer a Nutritious Meal

    Before heading to the doctor, give your child a healthy meal or snack that includes a balance of fruits, vegetables, proteins, and whole grains. This provides the energy their body needs to handle the vaccine, while keeping blood sugar stable helps prevent any lightheadedness or nausea after the shot. Avoid sugary snacks, which can lead to energy crashes.

    3. Ensure They Get Plenty of Sleep

    A good night’s sleep before vaccination day is crucial. When your child is well-rested, their immune system is better equipped to respond to the vaccine. Try to stick to their usual bedtime routine, aiming for at least 9-12 hours of sleep depending on their age. Kids who are rested often recover faster from any post-vaccine discomfort.

    4. Soothe Their Anxiety

    It’s common for kids to feel nervous about getting shots. Help them manage their anxiety by explaining what will happen in a calm, reassuring way. Depending on their age, using distraction techniques like bringing a favorite toy or allowing them to watch a video during the shot can reduce stress. Reducing anxiety may even help minimize the body’s stress response, which can contribute to side effects like soreness or fatigue.

    5. Discuss OtC anti-inflammatory medication or Pain Relief Options with Your Pediatrician

    If your child tends to experience significant pain, fever, malaise, or fussiness after vaccines, talk to your pediatrician about whether over-the-counter medications like acetaminophen (Tylenol) or ibuprofen (Advil) are appropriate. These medications can alter the immune response, which may be beneficial to your child. Your doctor can advise you on the best approach if your child experiences side effects after the shot. I recommend children be premedicated if they have a history of reactions or if the family has a history of vaccine reactions.

    6. Discuss prescription anti-inflammatory medication or Pain Relief Options with Your Pediatrician

    If your child or family has had severe reactions in the past (for example a seizure or seizure-like episode), then one option is premedicating with OTC medicines (ibuprofen, acetaminophen, and an anti-histamine) and considering adding a steroid, such as dexamethasone or prednisolone/prednisone.

    7. Keep Your Child Active After the Shot

    After the vaccine, encourage gentle arm movements and normal activity. Physical movement can help ease any soreness at the injection site. For younger children, simple activities like playing or using their arm in daily tasks can promote circulation and reduce stiffness. Applying a cool compress to the injection site can also relieve discomfort.

    8. Plan for Extra Rest Time

    While many children bounce back quickly after vaccines, some may feel tired or achy. It’s a good idea to plan a low-key day after their vaccination, giving them the chance to rest if needed. Mild symptoms like fatigue, a low-grade fever, or crankiness are common and generally short-lived, but ensuring your child has time to rest can speed recovery.

    9. Monitor and Comfort

    After the vaccine, keep an eye on how your child is feeling. If they develop a mild fever, make sure they continue to drink fluids and rest. Comfort them with extra cuddles or a favorite blanket, as physical reassurance can help them feel better. Most side effects, such as a slight fever or sore arm, go away within a day or two, but don’t hesitate to reach out to your pediatrician if you have concerns about your child’s reaction.

    Final Thoughts

    Vaccines are key to keeping your child healthy, and while mild reactions are common, these steps can help make the experience easier for both you and your little one. From staying hydrated to offering comfort and rest, preparing ahead of time can minimize any discomfort and help your child recover quickly. If you have any questions or worries about vaccines, don’t hesitate to discuss them with your pediatrician.

    Helping Kids Cope After Hurricane Helene: A Guide for Families

    The aftermath of Hurricane Helene can be overwhelming for families, especially for children who may not fully understand what has happened. As a pediatric practice, Canopy Pediatrics is here to support you and your children during this challenging time. Here are some ways families can help their kids cope with the emotional and psychological impacts of the hurricane.

    1. Create a Safe Space

    Establish a calm environment at home where your children can feel secure. Encourage them to express their feelings about the hurricane, whether through words, art, or play. Listening to their concerns without judgment can help them process their emotions.

    2. Maintain Routines

    Children thrive on routine, so try to keep their daily schedule as normal as possible. The includes morning and bedtime routines. This can provide a sense of stability amid the chaos. Incorporate activities that your child enjoys to help distract them from stress.

    3. Educate and Communicate

    Talk to your children about the hurricane in an age-appropriate manner. Explain what happened and reassure them that they are safe now. Open communication can help alleviate fears and misconceptions.

    4. Encourage Expression

    Allow your children to express their feelings. This could be through drawing, writing, or talking. Validate their emotions by acknowledging that it’s okay to feel scared, sad, or confused.

    5. Seek Professional Help

    If your child is showing signs of prolonged distress, consider reaching out to a mental health professional. There are many psychologists in Tallahassee who can provide support. Here are a few resources you might find helpful:

    These professionals can offer coping strategies and additional support tailored to your child’s needs.

    6. Access Medical Care if Needed

    In case your child requires medical attention, whether for physical or emotional health, don’t hesitate to reach out for help. For adult medical care, Access Direct Primary Care can provide immediate care and support.

    Conclusion

    Hurricane Helene has left a significant impact, but with love, support, and the right resources, families can help their children navigate this challenging time. Remember that you are not alone—Canopy Pediatrics is here to support you and your family through every step of recovery.

    For more information on how we can assist, visit our website at Canopy Pediatrics. Together, we can foster resilience in our children and help them thrive even after adversity.

    Omicron Update

    Omicron Is Headed Our Way…

    I hope that everyone has a Merry Christmas and a Happy New Year!  It looks like the new Omicron COVID-19 variant will be hitting Florida hard within the next 30 days, so I just want everyone to be ready.

    HOW OMICRON SEEMS TO BE DIFFERENT:

    *Key Take-Aways:
    1. Omicron is more contagious
    2. A surge may come early January
    3. Getting a booster vaccination is now more important

    Omicron Is Already In 47 States


    Omicron already accounts for 13% of COVID cases in the states of New York and New Jersey.

    A Florida Surge Is Probably Coming Early January

    This is according the largest hospital group in America, HCA.  This means that cases will be on the rise during Christmas.

    Two Times More Contagious Than The Delta Variant

    You probably heard that Delta was much more contagious than the earlier COVID strains, well Omicron is even more contagious!  Practically, this means that it will take less contact with a sick person to contract Omicron.  Omicron will spread faster through our businesses, schools, and families.

    A Shorter Incubation Period

    The “incubation period” is the how long it takes someone to show symptoms after they catch the virus from someone.  Delta was quicker than earlier variants, and Omicron is even faster.  With Omicron, people are showing symptoms within 1 to 4 days.  On the bright side, this means we won’t have to sit around waiting after exposures.  But this also means that large populations of people will all be getting sick at the same time, which could be overwhelming for our healthcare system.

    Possibly Less Severe Disease

    The data out of South Africa (where Omicron seems to have started) suggests that Omicron may not cause as serious disease as earlier variants.  But, South Africa’s population is younger, which could be the reason people are less sick than expected.  There is also some research showing that Omicron divides very fast in the nose, but slower than previous variants in lungs (so less breathing problems).  Let’s hope that this early information is all true and Omicron turns out to be less severe.

    Vaccines Continue To Prevent Serious Illness

    While our current vaccines are not as effective against Omicron, they still seem to be preventing hospitalizations and serious disease (but they may prevent transmission if with a booster dose).

    Being “Fully Vaccinated” (2 Pfizer or Moderna shots or 1 J&J) Does Not Prevent Infection OR Transmission of Omicron

    There are many documented cases of fully vaccinated people contracting Omicron and quickly infecting other people.  But again, vaccines are still doing a good job at preventing serious disease.  But, getting a booster shot can boost a person’s antibodies to the level that may prevent infection and transmission.

    A Vaccine Booster Is Even More Important

    A booster dose (a third dose of the Moderna or Pfizer mRNA vaccine) appears to increase antibody levels to the 80 to 90% effectiveness range for Omicron, possibly preventing infection and transmission.  This has led several countries to recommend earlier booster dosing.  The CDC currently recommends that a booster be given 6 months after the 2nd mRNA vaccine, but the UK (England) is now recommending adults receive a booster 2 months after the 2nd Moderna or 2nd Pfizer vaccine.  Israel is now recommending a 4th dose. The CDC says that the booster dose can be from either vaccine (mixing and matching is okay for a booster dose).

    The CDC currently recommends that immunocompromised individuals receive a 3rd Pfizer or Moderna vaccine 28 days after their 2nd shot.  The CDC is calling this an “Additional Primary Shot”

    For those whom initially received the Johnson & Johnson vaccine, the CDC is recommending a booster dose of Pfizer of Moderna two months after their J&J shot.

    How To Be Prepared At Home

    Dr. Sparks and I will always be available for our members, but you may want to order rapid home COVID test kits and a pulse oximeter to use at home–especially for parents, family, and friends.  For members, we will have plenty of rapid tests available at the office and send-out 48 hours PCR tests.

    Should We Change How We Are Living?

    Every family has their own comfort levels, and we all need to be back in society interacting and socializing.  I definitely recommend getting a booster shot ASAP and paying attention to the news.  If Omicron surges, there is a good chance many businesses and schools will go back to mask wearing for a temporary period.  If you or someone in your family is medically vulnerable, I would consider decreasing your social interaction during the surge.

    I have been living life more freely, usually without a mask, but I am personally getting ready to go back to masking-up and being more careful with my social interactions.  Also remember that masking is much better at preventing sick people from spreading COVID (because the sick person is wearing a mask), than preventing masked people from getting COVID from an unmasked sick person.

    What About The Holidays?

    There is a good chance that many of us will be getting together with people who have been exposed to Omicron. I would encourage family members to avoid gatherings if they have cold symptoms, such as fever, cough, sore throat or runny nose, and I would also encourage family members to get tested before gathering together for the holidays.  Last, encourage eligible family members to get their booster shots.

    Vaccines For Ages 6 Months Through 4 Years-Of-Age Are Delayed

    For several weeks now, children ages 5-11 have been able to receive the Pfizer COVID-19 vaccine at a lower dose (1/3 the adult dose).  With Omicron on the horizon, it is more important now than before for children of this age group to be vaccinated.  While kids usually get less severe infection than adults, it does seem like with each strain kids are becoming more susceptible to COVID-19.

    Pfizer released data on its vaccine trial for children ages 6 months to 4 years on Friday.  They used 1/10th of the adult dose.  There was a good immune response in children ages 6 months through 24 months after 2 doses, but not in children ages 2 to 4 years of age.  It appears that Pfizer has decided to add a third dose to all ages, 6 months through 4 years of age, and not try to release the vaccine for any children under 5 until after this trial.

    I have many families that were really hoping that the 6 month through 4 years-of-age vaccine would be released in January or February of 2022, but I am sad to say that it looks like mid-summer is more realistic, now that Pfizer is adding the third dose to all ages.

    Still Accepting New Members

    If you are interested in learning more about my concierge practice, Canopy Pediatrics, please text me at 850-701-9652 or email me at rhoman@canopypediatrics.com

    Hopefully this wave will be shorter than previous waves, since Omicron spreads faster, but let’s also hope that we do not overwhelm our health system!

    Dr. Russell Homan, MD

    What is so bad about RSV?

    One of the “strongest” cold viruses

    RSV (Respiratory Syncytial Virus) is one of the worst “common cold” viruses in circulation. 1 in 20 children under 3 months-of-age who contract RSV will require hospitalization. It is also very dangerous for the elderly and immunocompromised. Symptoms can last up to a month and many children shed the virus for 2 to 3 weeks (it’s very contagious). People “catch” RSV by touching their eyes, mouth, or food that has been in contact with RSV secretions or mucous (yuck). So handwashing is very important!

    The 2021 RSV Season is Late

    Because of COVID, adults and children were staying separate and wearing masks this winter, so the 2021 RSV started late and is continuing later than normal. Usually, RSV season would be over by now.

    RSV Goes to the Lungs

    Most “common cold” viruses cause coughing because of a postnasal drip and inflammation of the throat. But RSV often moves down into the lungs, causing wheezing, trouble breathing, and possibly requiring oxygen.

    How to Prevent RSV

    Since there is not an RSV vaccine yet, the best way to prevent RSV is to limit possible exposure. During RSV season, make sure infants and toddlers are kept away from sick children and adults. Also, since it’s mainly spread through mucous or secretions, handwashing is very important! Daycares and preschools should send home infants and toddlers with cold symptoms, especially during an RSV outbreak.

    How to Treat RSV

    Since RSV is a virus, there is no medical treatment for RSV. But children with RSV can develop ear infections, bacterial pneumonia, or sinus infections. As with all “colds” follow-up with your child’s pediatrician if you are concerned about your child.

    You Can Catch RSV Multiple Times

    Theoretically, someone could catch RSV every winter! Thankfully, the infections is usually milder with each infection.

    Medical Options For Allergy Symptoms

    It’s that time of the year! Many of us are walking around like zombies: groggy, stuffy nose, headache, sore throat, and itchy eyes. There is a lot that can be done, and much with over-the-counter (OTC) medications. You don’t have to continue in a state of pollen zombiness. The following is what I recommend for my patients.

    Most of people only know about sedating (ex. Benadryl) or non-sedating antihistamines (ex.’s Claritin, Zyrtec, or Allegra). “Sedating” means they cause sleepiness, and I think most people know that Benadryl can make you sleepy. But there are now many more options now, but we’ll start with the basics.

    For Mild to Moderate Nasal Congestion, Sneezing, or Sore Throat:

    • Non-Sedating Antihistamines: I recommend always starting with a non-sedating antihistamine. They rarely make people sleepy, they work quickly, and they usually last all day. Examples are loratadine (Claritin), cetirizine (Zyrtec), or fexofenadine (Allegra). Zyrtec is approved for children down to 6 months of age (but talk to your doctor first when giving it to a child less than 2 years of age).
    • Non-Sedating Antihistamines plus Nasal Decongestants: Two nasal decongestants, psuedoephedrine (Sudafed) and phenylephrine, can be combined with allergy medications. Pseudoephedrine works well, but it must be purchased at the pharmacy desk, because it can be abused as a stimulant or used in the production of methamphetamines. I recommend only using decongestants for short periods, such as 1 to 2 weeks at a time, and avoiding their use in the afternoon or at night, because they can cause trouble sleeping. There are many medical conditions in which decongestants should not be used, so if you have a medical condition (besides allergies) speak to your doctor before using one.
    • Sedating Antihistamines (i.e. Bendaryl): I would only recommend Benadryl (diphenhydramine) if you only have trouble with allergies at bedtime. Benadryl only lasts 6 hours and makes you sleepy.

    If Antihistamines Do Not Work or for Moderate to Severe Nasal Congestion and Sore Throat

    • Nasal Steroid Sprays: For the majority of people, nasal steroid sprays are sufficient to manage symptoms. Examples are Flonase (fluticasone), Rhinocort (budesonide), or Nasocort (Triamcinolone). I recommend fluticasone as it is a “2nd generation” spray, so less than 1% of the medication enters your body (as opposed to 10 to 50% of the older sprays, like triamcinolone or budesonide). Flonase “Sensimist” is approved for children down to 2 years-of-age.
    • Cromolyn Nasal Sprays: Cromolyn nasal sprays are probably the safest allergy medicines available, it’s just that you need to use them 3 to 4 times per day. One brand is Nasalcrom. They don’t work as well as nasal steroid sprays, but they are so safe, I often suggest using them in infants (only try under the guidance of your pediatrician).

    Prescription Options: If the oral antihistamines and/or Nasal Steroid Sprays do not work

    • Singulair (Montelukast): Many kids (and some adults) do not like having something sprayed up their noses. In these cases, I usually prescribe my patient Singulair. It’s approved for children down to 6 months-of-age. Sometimes Zyrtec (or Claritin) + Singulair is the perfect solution. Singulair also prevents wheezing in people with asthma.
    • Antihistamine Nasal Sprays: This is basically like spraying Benadryl right into your nose, and they work great for some people, especially people that have adverse effects from other medications.
    • Combination Steroid/Antihistamine Nasal Spray (Dymista): Some people (or children) find relief using both a nasal steroid spray AND an antihistamine nasal spray. There is even one spray, Dymista, that combines the two.

    Eye Symptoms: Dry, Itchy, Red, Watery Eyes

    • Newer Antihistamine Drops: The drops work very and are safe, and all but one, “ketotifen” require a prescription. Ketotifen can be found under the brand name “Zaditor,” “Alaway,” or other names. Make sure you check for the active ingredient. It can burn a little when it goes it, but storing the bottle in the refrigerator can help.
    • Oral antihistamines: The the sedating (Benadryl) and non-sedating (like Zyrtec) also help with eye allergy symptoms.
    • Older Antihistamine + Anti-Red Eye Combinations: These don’t work as well as the newer antihistamine eye drops (like ketotifen), but are the most common drops that you will find in the store. These will be under the brand names Naphcon-A, Opcon-A, Visine-A. If you use these for more than 2 weeks, your eye will start to become red between doses.

    Summary – For mild symptoms, start with Zyrtec (or similar). For moderate symptoms, start with a nasal steroid spray, like Flonase.

    If you cannot get your allergies under control, I recommend contacting your doctor, because he or she can help you find the right mix of prescription and non-prescription medications to get you and your family outside enjoying the Tallahassee spring and summer.

    The Race for 2021: COVID-19 vs the Vaccines

    I think we are all incredibly happy to get 2020 behind us, and I hope that 2021 is a much better year. As far as COVID goes, we finally have vaccines and doctors are better at keeping COVID patients out of the ICU. But still, COVID will give 2021 a challenging start for a few reasons:

    Challenges:

    1. COVID-19 ER visits and hospitalizations in Tallahassee have surpassed the previous July peak, forcing our hospitals to open new COVID-19 wards.
    2. A 50% more contagious COVID-19 strain is now circulating in the United States.
    3. Vaccine distribution is progressing more slowly than expected.
    4. About 25% of adults infected by COVID-19 still have symptoms 6 to 8 weeks later, many for months.

    Positives:

    1. Two COVID-19 vaccines have been licensed and distributed and many more are on the way.
    2. Death and the need for ICU beds from COVID-19 is still an issue, but it is decreased from early 2020.

    The End is Near, but We Need to Buckle Down

    Then end is near, but I believe things will get worse before getting better. People are getting tired of social distancing, and we are now seeing an increase in COVID-19 cases from families getting together over Thanksgiving, Christmas, and New Year’s. And there is a new, more contagious viral strain circulating. We are also continuing to learn more about COVID-19 “long-haulers” who experience symptoms of Post-COVID-19 Syndrome for weeks (sometimes even months) after their initial infection.

    If we can continue to be diligent with social distancing and limit unnecessary exposure to other people and families, many less people will contract COVID-19. As a society, we will be much better off once more of us are vaccinated.

    Many of Us Must Continue Living with a Significant Amount of COVID Exposure

    Still, most of us must continue living with a significant amount of COVID-19 exposure. I must continue to treat patients. Many people must work in-person. Some kids cannot succeed with distance learning and need to be in school. Some parents must send their kids to school or daycare so that they can work to put food on the table. But, we can all continue to be disciplined, and limit unnecessary exposures.

    If vaccines are released to the public by this summer (as expected), we could have a very normal fall! Hang in there another 6 months! This definitely encourages me to be extra careful for the coming months.

    Some Practical Social Distancing Reminders:

    1. Eating with people: I see this all the time. If you sit down to eat with people, especially inside, then you have just exposed yourself and your family to everyone these people have exposed themselves to. If you really need to eat with someone, try to find a table outside, which is much safer (but not perfectly safe).
    2. Exposure time: The amount of time you spend exposed to COVID-19 really matters. Quickly checking-out at a cash register or passing people in an isle is much different than working next to someone for an hour or two.
    3. Masks are not perfect: Masks are helpful as they block COVID-19 droplets from directly reaching people, but COVID-19 virus particles also sneak around the sides of the mask (or through the mask material), float in the air, and then get breathed in by nearby people.

    And remember, it just takes one exposure! I have heard many stories about families that had been very careful, but then let down their guard just once and got COVID. They may have gone to a wedding (where people were not masked), ate with a friend (who was not as careful as them), or spent extended face-to-face time with someone.

    I Got The COVID-19 Vaccine!!

    YESSSSSSSSSS! I am so glad this day is here! For me, getting a COVID-19 vaccine is like getting into college or getting a new car, it’s such a gamechanger! I am so thankful for TMH getting me in on day 1 in Tallahassee, Florida. And thank you to private industry for finding a solution to the COVID-19 Pandemic.

    If you have any doubts about the safety of COVID-19 please read my previous blog posts. As a general pediatrician, I did a lot of reading, and the more I read, the more I wanted a COVID-19 vaccine. Yes, I may get a little soreness or a fever, but THIS IS PART OF THE VACCINE DESIGN. If the vaccine didn’t elicit any inflammation, then the body would not make antibodies against the COVID-19 spike protein.

    Hopefully the general public will be vaccinated soon! I did not expect the vaccine to arrive until 2021!!!!!!!!

    Give Me A Vaccine, So That I Can Avoid Post Covid-19 Syndrome

    Blog 4 of the 4 Part Series: Why I Want a COVID-19 mRNA Vaccine (and why you should too).

    This is the fourth of four blog posts where I share what I have learned as a Tallahassee pediatrician doing my own research, and why I am excited to receive a COVID-19 vaccine:

    1. Sunday, December the 6th – How vaccines use our immune system to protect us against viruses, bacteria, and even cancer.
    2. Last Wednesday – How mRNA and DNA vaccines are different than traditional vaccines.
    3. Last Saturday – mRNA and DNA vaccine safety in animals and humans.
    4. Today – Post Covid-19 Syndrome
    For Young and Middle Age Adults, Post COVID-19 Syndrome May Cause More Suffering Than Acute Symptoms

    Even though I turned 40 in 2020 (yes, I know I look 25…except for the hair), I am not as nervous about the immediate effects of COVID-19 (fever, trouble breathing, etc.), as I am about the chronic effects of COVID-19.

    Very few people my age actually die from COVID-19, even though many will have flu-like symptoms for over a week or be hospitalized. But now, doctors and scientists are learning that some people will develop chronic COVID-19 symptoms for months, the most common symptom being fatigue, like having Mono, but worse. Others will suffer from shortness of breath, headaches, depression, brain fog, high blood pressure, cholesterol issue, or body aches. Some people alternate feeling fine for a week and then terrible for a week. This diverse group of chronic symptoms has been given the name, “Post COVID-19 Syndrome.”

    It would suck to be sick for a few weeks, but it would be even worse to be tired and have body aches for months or years.

    Post COVID-19 Syndrome May Be Caused by Damage to Small Blood Vessels

    Doctors and scientists are not sure how COVID-19 causes these persistent symptoms, but they think it is from damage to small blood vessels throughout the body–in the heart, lungs, liver, and even the brain. COVID-19’s damage to small blood vessels can cause stroke and heart attacks in relatively young patients (even in patients younger than myself). As you can imagine, blood vessels are found throughout the body, so this may be why the symptoms are so diverse, ranging from depression to trouble breathing.

    New Vaccine vs COVID-19 Infection

    To me the answer is clear: I would rather take a new(ish) vaccine than get a COVID-19 infection (or a second COVID-19 infection). These new vaccines have already been given to thousands of people without serious side-effects, while we know that COVID-19 can cause death, make you very sick for weeks, and can have long-term side-effects for months and maybe years.

    If you are skeptical about the Moderna and Pfizer/BioNTech vaccines, please read my previous posts. The more I learned about them, the more I wanted one!

    mRNA and DNA Vaccines in Humans and Animals

    Blog 3 of the 4 Part Series: Why I Want a COVID-19 mRNA Vaccine (and why you should too).

    This is the third of four blog posts where I share what I have learned as a Tallahassee pediatrician doing my own research, and why I am excited to receive a COVID-19 vaccine:

    1. Last Sunday – How vaccines use our immune system to protect us against viruses, bacteria, and even cancer.
    2. Last Wednesday – How mRNA and DNA vaccines are different than traditional vaccines.
    3. Today – mRNA and DNA vaccine safety in animals and humans.
    4. This Wednesday December the 16th – Post Covid-19 Syndrome
    The History of mRNA and DNA Vaccines

    Starting around 1990, scientists were first able to inject genetic material (mRNA or DNA) into animal muscle AMD get the muscle cells to produce a protein based on this genetic material.  This laid the foundation for mRNA and DNA vaccines, which stimulate the muscle cells near the injection to produce the antigen for the vaccine.  So far, the biggest challenge with DNA and mRNA vaccines has not been safety but getting them to work.  Scientists have continued to tweak the antigen code and the adjuvant effect of the DNA and mRNA.  They have also discovered better ways of getting the mRNA or DNA into the cells. 

    DNA and RNA Vaccines in Humans and Animals

    Though the new COVID-19 mRNA and DNA vaccines will be the first fully licensed vaccines for humans, there have been DNA vaccines licensed for animals since 2002.  This includes vaccines for fish, dogs, cats, horses, and chickens.  None of these licensed vaccines for animals have had to be pulled from the market for safety or efficacy concerns.

    mRNA and DNA Vaccines were already in Human Clinical Trials

    Starting 10 years before the COVID-19 pandemic, mRNA vaccines had started entering human clinical trials.  This includes vaccines against influenza, rabies, cancer, Mono, and Zika virus.  In fact, Moderna had already completed a successful Phase 1 Clinical Trial for an mRNA influenza vaccine in 2017. Most of the mRNA vaccines in trials have been safe and effective, but just like traditional antigen plus adjuvant vaccines, some mRNA vaccines were not effective and some had too strong of an immune response.  But after a decade of conducting mRNA vaccine trials on thousands of human lives, results have been so good and promising that research and interest has continued to grow.

    COVID mRNA Vaccines are 90-95% Effective, in Studies of Over 50,000 People

    I am so impressed with reports of 90 to 95% effectiveness.  Yes, the Phase 3 Clinical Trials are just finishing, and we only have about 9 months of safety data in humans, but 95% efficacy is awesome!  First, many vaccines and medications get to Phase 3 trials just to find out that they do not really work.  Second, this is exceeding the CDC’s goal for 70% effectiveness (the seasonal flu vaccine is only 40 to 60% effective every year).  95% Efficacy means that if you give 100 people the COVID-19 mRNA vaccine, and then expose them all to COVID-19, only 5 out of the 100 would contract COVID-19!

    COVID mRNA Vaccines have been Safe

    So far, COVID mRNA vaccines have been safe.  About 1/3rd of people who received the Moderna or Pfizer/BioNTech mRNA vaccines had a reaction.  Normally a little redness or swelling at the injection site or mild aches or fatigue.  About 2% (2 out of every 100 shots) of study participants had a “grade 3” reaction, which means that the fever, body aches, fatigue, or swelling was severe enough to keep the person from doing his or her normal activities for a day or two.  There were no life-threatening “grade 4” reactions in with either mRNA vaccine trial.  This is similar to what people experience after a Tdap (tetanus-diptheria-whooping cough) booster vaccine.

    What Other Adverse (aka Bad) Reactions were Scientists Worried About? 

    Some scientists were worried about too strong of an immune response from the adjuvant part of the mRNA.  This could have led to high fevers, inflammation, damage of vital organs, or too much swelling at the injection site  Thankfully, even though the mRNA immune response has been strong (which is good because it stimulates the body to build antibodies), it has not been dangerously strong.  Again, the experience is similar to receiving a Tdap vaccine.

    Second, scientists were worried about “Vaccine Enhanced Disease,” where the vaccine makes the real infection worse rather than protecting against the infection.  There were some animal vaccine studies of the 2002 SARS Coronavirus (which is similar to COVID-19), in which the experimental vaccine made the SARS infection worse, so scientists were appropriately nervous about VED occurring with COVID-19 vaccination.  Thankfully this has not happened. Even when vaccinated people get COVID-19, the COVID-19 infection has been less severe, instead of more severe.  More great news!

    Third, DNA and mRNA are genetic material.  There is a theoretical concern that a DNA or mRNA vaccine could permanently insert foreign genetic material into our DNA, leading to health problems.  In the decades of DNA and mRNA vaccine experimentation, this has never happened in animal or human studies (but it could make a good movie).

    In conclusion, the COVID-19 mRNA vaccines appear to be very safe and very effective, despite the rapid development and challenges of making a new vaccine.  Thankfully, mRNA and DNA vaccines had been in development for decades and were ready to be produced when the COVID-19 Pandemic hit.

    I hope after reading this (long) blog, you are encouraged and excited about how our country can overcome this horrible illness.  Post with any questions, and read my next blog covering Post Covid-19 Syndrome.

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